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Thankfully medical research for mastocytosis and mast cells in general has exploded internationally in recent years. We're highlighting those articles of note based on needs and health complications currently escalating amongst patients and physicians sharing with MSC. We've been tracking medical research for over 10 years so this is a very small sample of some of the best articles in our library. This listing is subject to change occasionally.

Please click title links to access each to view/download/print. MSC documents are available for free distribution and sharing as open access. Any medical literature listed which is not owned by MSC is made available with permission of authors and publishers OR linked to direct source online.

Systemic Mast Cell Disease: An Update as of June, 2011:- Abstract with links to download full transcripts with slides of a medical lecture featuring Dr. Lawrence B. Afrin, M.D., Hematology/Oncology, hosted by MSC with Dr. Gary Sibbald at Women's College Hospital in Toronto, Ontario.

Case-Control Cohort Study of Patients' Perceptions of Disability in Mastocytosis. Plos One full article.Olivier Hermine1,2,3*, Olivier Lortholary3,4, Phillip S. Leventhal3, Adeline Catteau3, Frederique Soppelsa3, Cedric Baude3, Annick Cohen-Akenine3, Fabienne Palmerini3,4,6, Katia Hanssens3,4,6, Ying Yang4, Hagay Sobol6, Sylvie Fraytag5, David Ghez1,2, Felipe Suarez2, Stephane Barete1,7, Philippe Casassus3,8, Beatrice Sans9, Michel Arock10, Jean Pierre Kinet3, Patrice Dubreuil3,4,6, Alain Moussy3. May 28, 2008

Thousand Faces of Mastocytosis: Mistaken Medical Diagnoses, Patient Suffering & Gender Implications. Sev'er,A; Sibbald,G; D'Arville,C. Published by University of Toronto Press, 2009. Includes 10 patient cases reporting in their own words their experience with symptoms and the road to diagnosis.

WHO subvariants of indolent mastocytosis: clinical details and prognostic evaluation in 159 consecutive adults. Pardanani,A; Lim,K-H; Lasho,T.L; Finke,C.M; McClure,R.F; Li,C-Y; Tefferi,A. Blood Journal 2010 115: 150-151

Evaluation of the WHO criteria for the classification of patients with mastocytosis. Sanchez-Munoz, L; Alvarez-Twose, I; Garcia-Montero, AC; Teodosio C; Jara-Acevedo, M; Pedreira, CE; Matito, A; Morgado, JM; Sanchez, ML; Mollejo, M; Gonzalez-de-Olano, D; Orfao, A; Escribano, L. Modern Pathology 24, 1157-1168 (September 2011)

Clinical correlates of blood serotonin levels in patients with mastocytosis. N. M. Kushnir-Sukhov,E. Brittain,L. Scott,D. D. Metcalfe. European Journal of Clinical Investigation 19 NOV 2008

Brain mast cell relationship to neurovasculature during development. Mona Khalil, Jocelyn Ronda, Michael Weintraub, Kim Jain, Rae Silver, and Ann-Judith Silverman. Brain Research Journal 23 January 2008

Evidence for Cognitive Impairment in Mastocytosis: Prevalence, Features and Correlations to Depression. Daniela Silva Moura,1,2* Serge Sultan,7,8 Sophie Georgin-Lavialle,1,3,4 Stéphane Barete,1,3,5 Olivier Lortholary,1,6 Raphael Gaillard,9,10 and Olivier Hermine1,13,11,12* PLoS One. 2012

Patterns of Skeletal Scintigraphy and Their Relationship to Plasma and Urinary Histamine Levels in Systemic Mastocytosis. Richard C. Rosenbaum, Marianne Frieri, and Dean D. Metcalfe. National Institutes of Allergy and Infectious Diseases. J Nucl Med 25:859-864; PUBLISHED 1984

Systemic Mastocytosis as a Cause of Severe Osteoporosis in a Young Woman. Liakou, Chrysoula MD*; Trovas, George MD*; Terpos, Evangelos MD; Papaioannou, Nikolaos Assoc. Prof* Endocrinologist: November/December 2010

Bone Mineral Content in Patients with Anaphylactic Reactions, Signs of Mastocytosis and Elevated Basal Serum Tryptase Levels. Christoph Bucher1,2, Daniel Uebelhart3, Brunello Wuthrich2, Jaap Swanenburg3 and Gerhard W. Goerres4. Open Allergy Journal, Switzerland, 2010.

Mutation D816V Alters the Internal Structure and Dynamics of c-KIT Receptor Cytoplasmic Region: Implications for Dimerization and Activation Mechanisms. Elodie Laine, Isaure Chauvot de BeauchĂȘne, David Perahia, Christian Auclair, Luba Tchertanov LBPA, CNRS - ENS de Cachan, Cachan, France. Published: June 16, 2011

Bone Marrow Biopsies for the Diagnosis of Systemic Mastocytosis. Is One Biopsy Sufficient? Joseph H. Butterfield, MD,1 and Chin-Yang Li, MD2. Am J Clin Pathol 2004

Systemic Mastocytosis Associated with Chronic Idiopathic Myelofibrosis, A Distinct Subtype of Systemic Mastocytosis-Associated Clonal Hematological Nonmast Cell Lineage Disorder Carrying the Activating Point Mutations KITD816V and JAK2V617F. Karl Sotlar, Anja Bache, Florian Stellmacher, Burkhard Bultmann, Peter Valent, and Hans-Peter Horny. Journal of Molecular Diagnostics, Vol. 10, No. 1, January 2008


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